BDBM50364541 CHEMBL1951011

SMILES CC(C)OC(=O)N1CCC(CC1)Oc1ncnc(Oc2ccc(cc2F)S(C)(=O)=O)c1C

InChI Key InChIKey=FEGPUMZPRQGWFH-UHFFFAOYSA-N

Data  1 KI  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50364541   

TargetGlucose-dependent insulinotropic receptor(Rat)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataEC50:  55nMAssay Description:Agonist activity at rat GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataEC50:  9.70nMAssay Description:Agonist activity at human GPR119 receptor assessed as cAMP production by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataEC50:  29nMAssay Description:Agonist activity at human GPR119 in HEK293 cells assessed as cAMP accumulation after 30 mins by CRE-beta-lactamase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50364541(CHEMBL1951011)
Affinity DataKi:  53nMAssay Description:Binding affinity to human GPR119 in HEK293FT cell membrane by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed