BDBM50364499 CHEMBL1950851

SMILES CN[C@@H](C)C(=O)N[C@H](C(=O)N[C@H]1CCCN(CCc2ccc(F)cc2)C1)C(C)(C)C

InChI Key InChIKey=AYWNCKNJOIZDHZ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50364499   

TargetBaculoviral IAP repeat-containing protein 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50364499(CHEMBL1950851)
Affinity DataEC50:  60nMAssay Description:Antagonist activity at cIAP1 in human MDA-MB-231 cells assessed as cIAP1 degradation after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetBaculoviral IAP repeat-containing protein 2(Human)
Astrazeneca R&D Boston

Curated by ChEMBL
LigandPNGBDBM50364499(CHEMBL1950851)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at GST-tagged BIR3 domain of cIAP1 using AbuRPFK-5FAM after 20 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed