BDBM50363956 CHEMBL1952025

SMILES Nc1ncnc2CCN(C(=O)c12)c1ccc(cc1)[C@H]1CC[C@H](CC(O)=O)CC1

InChI Key InChIKey=DVHSQIPHRVBFFO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363956   

TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human microsomal DGAT-1 expressed in baculovirus infected insect Sf9 cells using [14C]decanoylCoA as substrate after 1.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DGAT-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 71nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis in human HT-29 cells using [3H]glycerol as substrate after 6 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed