BDBM50363833 CHEMBL1945010

SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O)C(=O)NCCc1cc(OC)ccc1OC

InChI Key InChIKey=VOOYDDCVNCKBLQ-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50363833   

TargetType-1 angiotensin II receptor(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50363833(CHEMBL1945010)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetType-2 angiotensin II receptor(Human)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50363833(CHEMBL1945010)
Affinity DataIC50: 1.40E+3nMAssay Description:Displacement of [125I]Sar1 Ile8-Ang 2 from angiotensin 2 AT2 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
Beijing Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50363833(CHEMBL1945010)
Affinity DataKd:  3.16nMAssay Description:Antagonist activity at angiotensin 2 AT1 receptor in Japanese White rabbits thoracic aorta assessed as inhibition of KCl-indcuced contraction after 6...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed