BDBM50363494 5,5'-methylenebis(3,4,6-tribromo-benzene-1,2-diol) (4)::CHEMBL374829

SMILES Oc1c(O)c(Br)c(Cc2c(Br)c(O)c(O)c(Br)c2Br)c(Br)c1Br

InChI Key InChIKey=AMKNSMNMEAMKDN-UHFFFAOYSA-N

Data  4 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50363494   

TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 3.83E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the hydration of CO2 according to our previous studies [Soyut et al., Protein Pept. Lett., 15:52...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 680nMAssay Description:Inhibition of GST-tagged human recombinant PTB1B using pNPP as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of TCPTP after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SHP2 using OMFP as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SHP1 using OMFP as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase F(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of LAR using OMFP as substrate after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Jilin Province Academy of Traditional Chinese Medicine and Materia Medica

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataIC50: 566nMAssay Description:Inhibition of human muscle recombinant aldose reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataKi:  1.78E+4nMAssay Description:Inhibition of human carbonic anhydrase 6 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataKi:  2.15E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of human carbonic anhydrase 4 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Artvin£Oruh University

Curated by ChEMBL
LigandPNGBDBM50363494(CHEMBL374829 | 5,5'-methylenebis(3,4,6-tribrom...)
Affinity DataKi:  3.51E+4nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed