BDBM50363490 CHEMBL1946180::hCA inhibitor, 8

SMILES COc1c(Br)c(Br)c(CO)c(Br)c1OC

InChI Key InChIKey=VUMVVGRIGBOUHZ-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50363490   

TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  3.46E+4nMAssay Description:Inhibition of human CA2 using 4NPA as substrate for 3 mins by Lineweaver burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  4.64E+4nMAssay Description:Inhibition of human CA4 using 4NPA as substrate for 3 mins by Lineweaver burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  9.44E+4nMAssay Description:Inhibition of human carbonic anhydrase 2 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Artvin Coruh University

LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  1.93E+5nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Artvin Coruh University

LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  1.59E+5nMpH: 7.4Assay Description:CA activity was assayed by following the change in absorbance at 348 nm of 4-NPA to 4-nitrophenylate ion over a period of 3 min at 25°C using a spect...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/10/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Artvin Coruh University

LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  1.59E+5nMAssay Description:Inhibition of human carbonic anhydrase 6 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Artvin Coruh University

LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  1.93E+5nMAssay Description:Inhibition of human carbonic anhydrase 1 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Ataturk University

Curated by ChEMBL
LigandPNGBDBM50363490(CHEMBL1946180 | hCA inhibitor, 8)
Affinity DataKi:  1.04E+5nMAssay Description:Inhibition of human carbonic anhydrase 4 esterase activity using 4-nitrophenylacetate as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed