BDBM50363121 CHEMBL1946144

SMILES FCCOCCOCCOCCn1cc(CNC2(C(=O)NC(=O)NC2=O)c2ccc(Oc3ccccc3)cc2)nn1

InChI Key InChIKey=APJIPTNFOKEMIQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50363121   

TargetMatrix metalloproteinase-9(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363121(CHEMBL1946144)
Affinity DataIC50: 41nMAssay Description:Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363121(CHEMBL1946144)
Affinity DataIC50: 48nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363121(CHEMBL1946144)
Affinity DataIC50: 64nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate preinc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50363121(CHEMBL1946144)
Affinity DataIC50: 87nMAssay Description:Inhibition of MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed