BDBM50363073 CHEMBL1945981

SMILES COc1cc(cc(O)c1O)C(=O)Nc1ccc(cc1NC(C)=O)-c1ccccc1

InChI Key InChIKey=DRTNAOHQFUQPBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50363073   

TargetATP-dependent translocase ABCB1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50363073(CHEMBL1945981)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MDR1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMultidrug resistance-associated protein 1(Human)
University of Bari Aldo Moro

Curated by ChEMBL
LigandPNGBDBM50363073(CHEMBL1945981)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed