BDBM50362979 CHEMBL1945173

SMILES COc1ccc(CCCN(C)C)cc1Nc1ncc2CC(=S)Nc3cc(Cl)ccc3-c2n1

InChI Key InChIKey=JQRWYCWILFBHJT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50362979   

TargetMast/stem cell growth factor receptor Kit(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of KITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 590nMAssay Description:Inhibition of FLT3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 190nMAssay Description:Inhibition of PDGFRbMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 54nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50362979(CHEMBL1945173)
Affinity DataIC50: 140nMAssay Description:Inhibition of PLK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed