BDBM50362281 CHEMBL1939580

SMILES CCC(CC)c1cc(C)n2nc([nH]c(=O)c12)-c1ccc(OC)cc1C

InChI Key InChIKey=DDEPDGASNHZWBE-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362281   

TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362281(CHEMBL1939580)
Affinity DataEC50:  688nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO-K1 cells assessed as CRF-stimulated cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50362281(CHEMBL1939580)
Affinity DataIC50: 149nMAssay Description:Displacement of [125I]CRF from human CRF1 receptor expressed in CHO-K1 cells after 2 hrs by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed