BDBM50362204 CHEMBL1938845

SMILES CN1C[C@H]2CN(C[C@H]2C1)C(=O)c1nc2ccc(F)c(C)c2[nH]1

InChI Key InChIKey=UGGVOGPIDWSWJJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50362204   

TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50362204(CHEMBL1938845)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]histamine from human recombinant histamine H4 receptor expressed in CHO cells coexpressing Ga15 by radioligand filtration binding...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50362204(CHEMBL1938845)
Affinity DataKi:  97nMAssay Description:Antagonist activity at human histamine H4 receptor expressed in HEK293 cells assessed as rev inhibition of forskolin-stimulated cAMP accumulation by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed