BDBM50362070 CHEMBL1940114

SMILES COc1cccc(NC(=O)Cn2cc(Oc3ccnc4cc(OC)c(cc34)C#N)cn2)c1

InChI Key InChIKey=RDWQPGCGRCTSIN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362070   

TargetVascular endothelial growth factor receptor 3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362070(CHEMBL1940114)
Affinity DataIC50: 282nMAssay Description:Inhibition of VEGFR3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362070(CHEMBL1940114)
Affinity DataIC50: 2nMAssay Description:Inhibition of PDGFRbeta phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
LigandPNGBDBM50362070(CHEMBL1940114)
Affinity DataIC50: 50nMAssay Description:Inhibition of CSF1R phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50362070(CHEMBL1940114)
Affinity DataIC50: 40nMAssay Description:Inhibition of FLT3 phosphorylation by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed