BDBM50361758 CHEMBL1938495

SMILES Fc1ccc(cc1)C(NC(=O)CCN1CCC(CC1)c1nc(no1)-c1ccccn1)c1ccncc1

InChI Key InChIKey=NNKMOTYRUOEJOI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361758   

TargetLysosomal Pro-X carboxypeptidase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361758(CHEMBL1938495)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLysosomal Pro-X carboxypeptidase(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50361758(CHEMBL1938495)
Affinity DataIC50: 15nMAssay Description:Inhibition of PrCP-mediated conversion of Ang3 to Ang(2-7) in mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed