BDBM50361599 CHEMBL1939844

SMILES COc1ccc(cc1)S(=O)(=O)N1CC(=O)N(O)C(=O)[C@H]1C(C)C

InChI Key InChIKey=FTRCUXMVUJZMHT-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50361599   

TargetMatrix metalloproteinase-9(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant MMP9 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant MMP14 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of MMP1 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant MMP2 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of MMP3 using Mca-Arg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrilysin(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of MMP7 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 300nMAssay Description:Inhibition of human recombinant MMP8 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 66nMAssay Description:Inhibition of MMP12 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 300nMAssay Description:Inhibition of MMP13 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-16(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant MMP16 using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Instituto Superior T£Cnico

Curated by ChEMBL
LigandPNGBDBM50361599(CHEMBL1939844)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of TACE using Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 as substrate preincubated for 4 hrs measured every 15 secs for 20 mins by fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed