BDBM50361444 CHEMBL1938433

SMILES ONC(=O)C=Cc1ccc2OC3(CCN(Cc4ccccc4)CC3)CC(=O)c2c1

InChI Key InChIKey=PTSASYUIHCGRFT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50361444   

TargetHistone deacetylase 1(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 93.8nMAssay Description:Inhibition of HDAC1 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of HDAC3 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 127nMAssay Description:Inhibition of HDAC4 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 25.7nMAssay Description:Inhibition of HDAC6 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 1.76E+3nMAssay Description:Inhibition of HDAC8 using carboxyfluorescein-labeled peptide as substrate after 17 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Dac

Curated by ChEMBL
LigandPNGBDBM50361444(CHEMBL1938433)
Affinity DataIC50: 65nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed