BDBM50361254 CHEMBL1934896

SMILES Cc1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NO)cc1C

InChI Key InChIKey=FDDOLFDMTDIZNX-UHFFFAOYSA-N

Data  6 KI  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50361254   

TargetHistone deacetylase-like amidohydrolase(Alcaligenes sp. (strain DSM 11172) (Bordetella sp....)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  260nMAssay Description:Inhibition of Bordetella FB188 HDAH using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  8.80E+3nMAssay Description:Inhibition of recombinant human HDAC1 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  2.40E+4nMAssay Description:Inhibition of recombinant human HDAC6 using Boc-L-Lys(acetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  3.30E+3nMAssay Description:Inhibition of recombinant human HDAC7 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKd:  1.40E+4nMAssay Description:Inhibition of recombinant human HDAC8 using Boc-L-Lys(trifluoroacetyl)-MCA as substrate by fluorogenic enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human HDAC7 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human HDAC1 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  8.40E+3nMAssay Description:Inhibition of human HDAC8 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Applied Sciences

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition of human HDAC6 using Boc-Lys(Ac)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mins by trypsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC5 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Applied Sciences Darmstadt

Curated by ChEMBL
LigandPNGBDBM50361254(CHEMBL1934896)
Affinity DataKi: >5.00E+4nMAssay Description:Inhibition of human HDAC4 using Boc-Lys(trifluoroacetyl)-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2019
Entry Details Article
PubMed