BDBM50361222 CHEMBL1934351

SMILES NC(=O)CN1CCC(CC1)c1ccc(Nc2ncc3ccc(-c4cccc5cccnc45)n3n2)cc1

InChI Key InChIKey=SMOLATMZTWOLFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361222   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361222(CHEMBL1934351)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361222(CHEMBL1934351)
Affinity DataIC50: 167nMAssay Description:Inhibition of human recombinant FAK expressed in baculovirus expression system after 30 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361222(CHEMBL1934351)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed