BDBM50361219 CHEMBL1934348

SMILES NC(=O)CN1CCC(CC1)c1ccc(Nc2ncc3ccc(-c4cccc5OC(F)(F)Oc45)n3n2)cc1

InChI Key InChIKey=DZPFKGQUWAWYKE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361219   

TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361219(CHEMBL1934348)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetFocal adhesion kinase 1(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361219(CHEMBL1934348)
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant FAK expressed in baculovirus expression system after 30 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50361219(CHEMBL1934348)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant JAK2 expressed in baculovirus expression system after 20 mins by time resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed