BDBM50361161 CHEMBL4170388::US12325725, Compound 5

SMILES [H][C@@]12CC=C(c3ccc4c(N)n[nH]c4c3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

InChI Key InChIKey=XNVCTRGKURQQID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361161   

TargetCyclin-dependent kinase 8(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50361161(CHEMBL4170388 | US12325725, Compound 5)
Affinity DataIC50: 1.52E+3nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8/19(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50361161(CHEMBL4170388 | US12325725, Compound 5)
Affinity DataIC50: 1.35E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent