BDBM50361012 CHEMBL1935574

SMILES Nc1nc(N2CCNCC2)c2ccc(cc2n1)-c1ccco1

InChI Key InChIKey=UBEJREHBDACTGD-UHFFFAOYSA-N

Data  10 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50361012   

TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataIC50: 106nMAssay Description:Antagonist activity at human H4 receptor expressed in HEK293T cells assessed as inhibition of histamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  7nMAssay Description:Antagonist activity at human H4 receptor expressed in HEK293T cells assessed as inhibition of histamine-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Mouse)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]histamine from mouse H4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Rat)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  174nMAssay Description:Displacement of [3H]histamine from rat H4RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Mouse)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  1.07E+3nMAssay Description:Displacement of [3H]histamine from mouse H3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  2.56E+3nMAssay Description:Displacement of [3H]histamine from rat H3RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Mouse)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  3.30E+3nMAssay Description:Displacement of [3H]histamine from mouse H1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  3.41E+3nMAssay Description:Displacement of [3H]histamine from human H3 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  3.60E+3nMAssay Description:Displacement of [3H]histamine from rat H1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Griffin Discoveries

Curated by ChEMBL
LigandPNGBDBM50361012(CHEMBL1935574)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [3H]histamine from human H1 receptor expressed in HEK cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed