BDBM50360888 CHEMBL1935111

SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)CC1C

InChI Key InChIKey=CUMDJLVCVBQTKA-UHFFFAOYSA-N

Data  6 KI  10 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50360888   

TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataEC50:  1.40nMAssay Description:Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataEC50:  1.30nMAssay Description:Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  18nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50360888(CHEMBL1935111)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed