BDBM50360392 CHEMBL1933865

SMILES COc1ccc(\C=C(/C#N)c2nc3ccccc3[nH]2)cc1I

InChI Key InChIKey=FMGFJOARXWKCIE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50360392   

TargetBotulinum neurotoxin type A(Clostridium botulinum)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain-mediated SNAP-25 substrate cleavage after 40 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBotulinum neurotoxin type B(Clostridium botulinum)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Clostridium botulinum BoNT/B light chain after 40 mins by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Clostridium botulinum BoNT/A light chain after 40 mins by HPLC assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Microbiotix

Curated by ChEMBL
LigandPNGBDBM50360392(CHEMBL1933865)
Affinity DataIC50: 7.40E+4nMAssay Description:Inhibition of Bacillus anthracis lethal factor using MCA-KKVYPYPME[dnp]Kamide peptide substrate after 30 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed