BDBM50359954 CHEMBL1927088

SMILES COc1ccccc1N1CCN(CCCN=C(NC#N)c2ccccn2)CC1

InChI Key InChIKey=QDINHVYVESYLKG-UHFFFAOYSA-N

Data  7 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50359954   

Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataIC50: 0.00212nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  0.00157nMAssay Description:Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  1.61nMAssay Description:Displacement of [3H]mesulergine from Sprague-Dawley rat brain cortex serotonin 5-HT2C receptor after 15 mins by liquid scintillation counting in pres...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  4.68nMAssay Description:Displacement of [3H]-8-OH-DPAT from Sprague-Dawley rat brain cortex serotonin 5-HT1A receptor after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  20nMAssay Description:Binding affinity to alpha 1A adrenergic receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi:  22nMAssay Description:Binding affinity to 5-HT1A receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from rat corpora striatum dopamine D1 receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50359954(CHEMBL1927088)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from rat corpora striatum dopamine D2 receptor after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2012
Entry Details Article
PubMed