BDBM50359794 CHEMBL4162472::US12325725, Compound 7

SMILES [H][C@@]12CC=C(c3ccc4cn[nH]c4c3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

InChI Key InChIKey=CJAIHDIRDBQZLZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50359794   

TargetCyclin-dependent kinase 8(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50359794(CHEMBL4162472 | US12325725, Compound 7)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2020
Entry Details Article
PubMed
TargetCyclin-dependent kinase 8/19(Human)
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM50359794(CHEMBL4162472 | US12325725, Compound 7)
Affinity DataIC50: 6.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/4/2025
Entry Details
Go to US Patent