BDBM50359648 CHEMBL1929036

SMILES Cc1ccccc1-n1nc(cc1-c1ccc2OCC(=O)Nc2c1)C(F)(F)F

InChI Key InChIKey=CMFFEQLOOLNLFE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50359648   

TargetProgesterone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359648(CHEMBL1929036)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]progesterone from PRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359648(CHEMBL1929036)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human MR transfected in human COS1 cells after 1 day by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359648(CHEMBL1929036)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]testosterone from ARMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMineralocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359648(CHEMBL1929036)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]aldosterone from cytosolic human MR expressed in HEK293 cells after 16 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50359648(CHEMBL1929036)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [3H]dexomethasone from GRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed