BDBM50359331 CHEMBL1929210

SMILES CC(C)(C)c1cc(n(n1)CC(=O)N2CCS(=O)(=O)CC2)NC(=O)Nc3ccc4ccccc4c3

InChI Key InChIKey=ZTXJXRZDKINTFZ-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50359331   

TargetMitogen-activated protein kinase 14(Human)
Ansaris

Curated by ChEMBL
LigandPNGBDBM50359331(CHEMBL1929210)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into GST-ATF2 substrate preincubated for 20 mins before substrate addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 11/12/13/14(Human)
University of Zagreb

Curated by ChEMBL
LigandPNGBDBM50359331(CHEMBL1929210)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MAPK p38 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)