BDBM50359261 CHEMBL1923617

SMILES CC[C@H](C)[C@@H]1NCCOc2ccccc2CCCNC(=O)[C@@H](Cc2ccc(Cl)cc2)NC(=O)[C@@H](C)N(C)C1=O

InChI Key InChIKey=UKTFKKQZZNIQCZ-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50359261   

TargetGrowth hormone secretagogue receptor type 1(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50359261(CHEMBL1923617)
Affinity DataEC50:  14nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAppetite-regulating hormone(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359261(CHEMBL1923617)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human GRLN receptor expressed in HEK293 cells assessed as calcium binding by Ca2+ bioluminescence aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAppetite-regulating hormone(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359261(CHEMBL1923617)
Affinity DataKi:  0.350nMAssay Description:Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50359261(CHEMBL1923617)
Affinity DataKi:  1nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed