BDBM50359255 CHEMBL1923501

SMILES CCC[C@@H]1NCCOc2ccccc2\C=C\CNC(=O)[C@@H](Cc2ccccc2)NC(=O)CN(C)C1=O

InChI Key InChIKey=RWYUFLWFQCYBIM-UHFFFAOYSA-N

Data  1 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359255   

TargetAppetite-regulating hormone(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359255(CHEMBL1923501)
Affinity DataEC50:  134nMAssay Description:Agonist activity at human GRLN receptor expressed in HEK293 cells assessed as calcium binding by Ca2+ bioluminescence aequorin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Universite£

Curated by ChEMBL
LigandPNGBDBM50359255(CHEMBL1923501)
Affinity DataEC50:  68nMAssay Description:Agonist activity at ghrelin receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAppetite-regulating hormone(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50359255(CHEMBL1923501)
Affinity DataKi:  86nMAssay Description:Displacement of [125I-His9]-ghrelin from human GRLN receptor by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed