BDBM50359216 CHEMBL1923311

SMILES CCN1C2=NC(C)(C)CN2c2c(nc(-c3ccc(cc3)-c3ccccc3)n2Cc2ccc(F)cc2F)C1=O

InChI Key InChIKey=PGPJDKRNKQKAGH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359216   

TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359216(CHEMBL1923311)
Affinity DataIC50: 700nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed