BDBM50359213 CHEMBL1923308

SMILES CCN1C2=NC3(CN2c2c(nc(-c4ccc(cc4)-c4ccccc4)n2Cc2ccc(F)c(F)c2)C1=O)CCCCC3

InChI Key InChIKey=VUUBRRYURVLMBZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359213   

TargetP2X purinoceptor 7(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50359213(CHEMBL1923308)
Affinity DataIC50: 388nMAssay Description:Antagonist activity at P2X7 receptor in LPS-stimulated human whole blood assessed as inhibition of ATP-induced IL1-beta production treated 30 mins be...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed