BDBM50359154 CHEMBL1922974

SMILES Cn1cc(C=c2c(=O)[nH][nH]\c2=c2/snnc2=C)c2c(OCc3c(F)ccc(Cl)c3F)cccc12

InChI Key InChIKey=WDFURCPOBHRTIU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359154   

TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359154(CHEMBL1922974)
Affinity DataIC50: 400nMAssay Description:Inhibition of nucleophosmin-fused ALK autophosphorylation in human Karpas299 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetInsulin receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359154(CHEMBL1922974)
Affinity DataIC50: 861nMAssay Description:Inhibition of GST-tagged intracellular domain of IR by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50359154(CHEMBL1922974)
Affinity DataIC50: 5nMAssay Description:Inhibition of ALKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed