BDBM50359050 CHEMBL1922513

SMILES CCCCCCCCn1sc2ccccc2c1=O

InChI Key InChIKey=WVGPLHUTLSZSGX-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50359050   

TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of human recombinant MAGL assessed as [3H]oleoylglycerol hydrolysis after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 660nMAssay Description:Inhibition of human recombinant MAGL assessed as inhibition of 2-oleoylglycerol hydrolysis preincubated for 10 mins by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 59nMAssay Description:Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 3.52E+4nMAssay Description:Inhibition of human recombinant FAAH assessed as conversion of [3H]AEA to [3H]ethanolamine after 10 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant rat MGL expressed in human HeLa cells using 2-oleoylglycerol as substrate preincubated for 10 mins followed by substrate ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed