BDBM50358931 CHEMBL1923700

SMILES C[C@H](NC(=O)c1cc(cc(c1)-c1nc2ccccc2[nH]1)N(C)S(C)(=O)=O)c1ccccc1

InChI Key InChIKey=GCCLLOMNKKXXOF-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50358931   

TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358931(CHEMBL1923700)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358931(CHEMBL1923700)
Affinity DataIC50: 2.13E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358931(CHEMBL1923700)
Affinity DataKi:  1.04E+3nMAssay Description:Inhibition of BACE1 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis-Menten equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50358931(CHEMBL1923700)
Affinity DataKi:  2.07E+3nMAssay Description:Inhibition of BACE2 expressing APP Swedish mutant using rhodamine-labeled EVNLDAEFK-quencher as substrate after 60 mins by Michaelis-Menten equationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed