BDBM50358773 CHEMBL1922600

SMILES Cn1nc(cc1C(=O)Nc1cccc(Nc2cc3c(cc2Cl)c(=O)[nH][nH]c3=O)c1)C(C)(C)C

InChI Key InChIKey=ZQEBCHADYFBOIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50358773   

TargetSerine/threonine-protein kinase B-raf(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50358773(CHEMBL1922600)
Affinity DataIC50: 293nMAssay Description:Inhibition of human recombinant his6-tagged B-Raf expressed in Sf9 cells assessed as inhibition of MEK1 phosphorylation after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed