BDBM50358567 CHEMBL1923729

SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)-c1ccc(=O)n(C)c1

InChI Key InChIKey=MCNAJLPLCULBOJ-UHFFFAOYSA-N

Data  5 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50358567   

TargetCytochrome P450 1A2(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataEC50:  0.700nMAssay Description:Inhibition of basal activity of human histamine H3 receptor expressed in CHO cells assessed as inhibition of RAHM-induced [35S]GTPgammaS binding afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataKi:  8.5nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H1 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetHistamine H4 receptor(Human)
Cephalon

Curated by ChEMBL
LigandPNGBDBM50358567(CHEMBL1923729)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed