BDBM50358323 CHEMBL1922582

SMILES CCCn1[nH]c(=O)c2cc(NC(=O)c3nc(oc3C(F)(F)F)-c3ccccc3)ccc12

InChI Key InChIKey=OUMKAVGLHVITRR-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50358323   

TargetDiacylglycerol O-acyltransferase 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358323(CHEMBL1922582)
Affinity DataIC50: 60nMAssay Description:Inhibition of human DGAT1 using palmitoyl-1-14C coenzyme A and DAG as substrate after 1 hr by phospholipid flash plate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Roche Research Center

Curated by ChEMBL
LigandPNGBDBM50358323(CHEMBL1922582)
Affinity DataEC50:  2.50E+3nMAssay Description:Inhibition of human DGAT1 expressed in CHOK1 cells using 14C palmitic acid as substrate after 1 hr by TLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed