BDBM50358166 CHEMBL1921842

SMILES NC(=O)c1ccc(Oc2ccc(CN3CCC[C@H]3c3cccnc3)cc2)c(Cl)c1

InChI Key InChIKey=LOOCZNLSXJHWTG-UHFFFAOYSA-N

Data  5 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50358166   

TargetKappa-type opioid receptor(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKd:  0.0280nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  0.720nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Xiamen University

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  0.722nMAssay Description:Displacement of [3H]diprenorphine from human opioid kappa receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]diprenorphine from human opioid mu receptor expressed in CHO cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  26nMAssay Description:Binding affinity to mu-opioid receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetDelta-type opioid receptor(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50358166(CHEMBL1921842)
Affinity DataKi:  153nMAssay Description:Displacement of [3H]diprenorphine from human opioid delta receptor expressed in HEK293 cells after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed