BDBM50357995 CHEMBL202780

SMILES CC(C)(CCCN1CC[C@@H]2CCCC[C@H]2C1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=ZKMMUOFYONDNCU-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357995   

Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]-5-CT from human 5-HT7 receptor expressed in HEK293 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  8nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT7 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  900nMAssay Description:Displacement of [3H]spiperone from the cloned human D2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1A receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H]ketanserin from the cloned human 5-HT2A receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetAlpha-1A/Alpha-1B/Alpha-1D adrenergic receptor(Rat)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi:  3.90E+3nMAssay Description:Displacement of [3H]prazosin from alpha-1 adrenergic receptor in rat cortexMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi: >4.00E+3nMAssay Description:Displacement of [35S]-labeled MK-499 from cloned human ERG receptor expressed in HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50357995(CHEMBL202780)
Affinity DataKi: >7.00E+3nMAssay Description:Displacement of [3H]5-HT from the cloned human 5-HT1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed