BDBM50357943 CHEMBL1916768

SMILES Nc1c2CCCCc2nc2n(c(cc12)-c1ccccc1)-c1ccccc1

InChI Key InChIKey=VRGOOLXPHWCIIA-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50357943   

TargetAcetylcholinesterase(Electric eel)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50357943(CHEMBL1916768)
Affinity DataIC50: 610nMAssay Description:Inhibition of Electrophorus electricus AChE using acetylthiocholine iodide as substrate preincubated for 10 mins before substrate addition by Ellman'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50357943(CHEMBL1916768)
Affinity DataIC50: 74nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 10 mins before substrate addition by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50357943(CHEMBL1916768)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human recombinant AChE using acetylthiocholine as substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCholinesterase(Human)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50357943(CHEMBL1916768)
Affinity DataIC50: 8.57E+3nMAssay Description:Inhibition of human serum BuChE using butyrylthiocholine as substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Lisbon

Curated by ChEMBL
LigandPNGBDBM50357943(CHEMBL1916768)
Affinity DataKi:  621nMAssay Description:Mixed-type inhibition of Electrophorus electricus AChE assessed as hydrolysis of acetylthiocholine by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed