BDBM50357361 CHEMBL1917102

SMILES [O-][N+](=O)c1ccc2c(c1)S(=O)(=O)N=S2c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=MRKWZKWCOFETNQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50357361   

TargetProstaglandin G/H synthase 2(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357361(CHEMBL1917102)
Affinity DataIC50: 500nMAssay Description:Inhibition of human recombinant COX2 expressed in Sf21 cells assessed as conversion of arachidonic acid to PGE2 preincubated for 15 mins measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50357361(CHEMBL1917102)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human 5-LOX in human PBML assessed as inhibition of A23187-induced LTB4 production preincubated for 15 mins measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed