BDBM50357290 CHEMBL1916697

SMILES COC(=O)N(Cc1ccccc1)Cc1cc(ccc1-c1cc(CC(O)=O)ccc1OC)C(F)(F)F

InChI Key InChIKey=WGXIPXHUOIQNGL-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50357290   

TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 22nMAssay Description:Inhibition of human prostanoid DP2 receptor in human whole bood assessed as eosinophil shape change preincubated for 15 mins before addition of PGD2 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]-PGD2 from human prostanoid DP2 receptor expressed in human 293T cells by liquid scintillation counting in presence of 0.2 % huma...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 1.26E+4nMAssay Description:Displacement of [3H]-PGD2 from human DP1 receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetThromboxane A2 receptor(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50357290(CHEMBL1916697)
Affinity DataIC50: 6.24E+4nMAssay Description:Displacement of [3H]-SQ-29,548 from human TP receptor expressed in human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed