BDBM50356906 CHEMBL1915555

SMILES OC(=O)Cn1nnc(n1)-c1cncc(c1)-c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1

InChI Key InChIKey=KFLRCBGJPSBTOG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356906   

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50: 56nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50: 694nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356906(CHEMBL1915555)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed