BDBM50356893 CHEMBL1915543

SMILES NC(=O)c1cn(Cc2cc(Br)c(Br)c(Br)c2)nn1

InChI Key InChIKey=LFBACDLGCJVAMX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50356893   

TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50: 19nMAssay Description:Inhibition of rat SCD by rat microsomal assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of SCD in rat hepatocytes assessed as conversion of [14C]-stearic acid to [14C]-oleic acid preincubated for 15 mins measured after 1 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetStearoyl-CoA desaturase(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50356893(CHEMBL1915543)
Affinity DataIC50: 760nMAssay Description:Inhibition of SCD in human HepG2 cells assessed as conversion of [1-(14)C]-stearic acid to (14)C-oleic acidMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed