BDBM50356435 CHEMBL1911585

SMILES Clc1ccccc1CSc1[nH]c(=O)c(C#N)c2CCCCc12

InChI Key InChIKey=VIGFZYHSUDPDBL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50356435   

Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356435(CHEMBL1911585)
Affinity DataIC50: 5nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356435(CHEMBL1911585)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]-cortisone to [3H]-cortisol by scintillation plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356435(CHEMBL1911585)
Affinity DataIC50: 3.51E+3nMAssay Description:Inhibition of 11beta-HSD1 in mouse 3T3L1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Bristol-Myers Squibb Research & Development

Curated by ChEMBL
LigandPNGBDBM50356435(CHEMBL1911585)
Affinity DataIC50: 78nMAssay Description:Inhibition of 11beta-HSD1 in human HEK cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed