BDBM50356428 CHEMBL1911572

SMILES CCN(CC)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1

InChI Key InChIKey=WZRPREYJPXVHGG-UHFFFAOYSA-N

Data  10 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50356428   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE5AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE11AMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE1BMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE2AMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE3AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE8AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE9AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE10AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
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TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Biocrea

Curated by ChEMBL

LigandBDBM50356428(CHEMBL1911572)Copy SMILESCopy InChI

Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant PDE4A4 expressed in baculovirus infected insect Sf21 cells after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL