BDBM50356071 CHEMBL1911822

SMILES CN1CCN(CC1)C(=O)[C@@H](COCc1ccnc(Cl)c1)NC(=O)c1cccnc1Oc1ccc(cc1Cl)C(F)(F)F

InChI Key InChIKey=ACYMETHQFZHOBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50356071   

TargetCeramide glucosyltransferase(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356071(CHEMBL1911822)
Affinity DataIC50: 50nMAssay Description:Inhibition of GCS assessed as amount of UDP-glucose consumed during enzyme-catalyzed reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Exelixis

Curated by ChEMBL
LigandPNGBDBM50356071(CHEMBL1911822)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes assessed as inhibition of oxidative metabolism of testosterone after 45 mins by MS analysis in the pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed