BDBM50355861 CHEMBL1909733

SMILES Brc1ccccc1-c1c[nH]nn1

InChI Key InChIKey=FMNFGAAZKHHVAD-UHFFFAOYSA-N

Data  1 KI  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50355861   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of human recombinant indoleamine-2,3-dioxygenase expressed in Escherichia coli BL21 using L-tryptophan as substrate after 30 mins by micro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of indoleamine-2,3-dioxygenase in human HEK293 cells assessed as N-formylkynurenine level after 5 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human IDO1 transfected in mouse P815B clone-6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human TDO transfected in mouse P815B clone 19 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of mouse TDO in P815 clone 12 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
Ludwig Center For Cancer Research of The University of Lausanne

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 34nMAssay Description:Inhibition of mouse IDO1 in P815 clone 6 cells by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataIC50: 6.40E+3nMpH: 6.5Assay Description:Inhibition of human recombinant N-terminal His-tagged IDO1 (Ala2 to Gly403) overexpressed in Escherichia coli BL21 at pH 6.5 after 60 mins by HPLC an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50355861(CHEMBL1909733)
Affinity DataKi:  1.80E+4nMAssay Description:Uncompetitive inhibition of human recombinant indoleamine-2,3-dioxygenase expressed in Escherichia coli BL21 using L-tryptophan as substrate by Dixon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed