BDBM50355676 CHEMBL1911013

SMILES FC(F)c1nc2c(cccc2n1-c1nc(nc(n1)N1CCOCC1)N1CCOCC1)C#N

InChI Key InChIKey=RWTPCDKVABLMHM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50355676   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Mouse)
University of Auckland

Curated by ChEMBL

LigandBDBM50355676(CHEMBL1911013)Copy SMILESCopy InChI

Affinity DataIC50: 61nMAssay Description:Inhibition of mouse recombinant PI3K p110alpha expressed in Sf21 insect cells using phosphatidylinositol as substrate after 1 hr by phosphoimagingMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
University of Auckland

Curated by ChEMBL

LigandBDBM50355676(CHEMBL1911013)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant PI3K p110beta expressed in Sf21 insect cells using phosphatidylinositol as substrate after 1 hr by phosphoimagingMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/20/2012
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL