BDBM50355313 CHEMBL1835116

SMILES NC(=Nc1ccc2c(c[nH]c2c1)C1CN2CCC1CC2)c1cccs1

InChI Key InChIKey=OHHGHMJEPXHYDM-UHFFFAOYSA-N

Data  13 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50355313   

TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 450nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 4.06E+4nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.39E+5nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 5.21E+4nMAssay Description:Inhibition of human recombinant iNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 2.33E+4nMAssay Description:Inhibition of human recombinant eNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant nNOS expressed in Sf9 cells assessed as inhibition of conversion of [3H]-L-arginine to [3H]-L-citrulline after 45 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 4.96E+4nMAssay Description:Inhibition of CYP2C19 using CEC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2D6 using AMMC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 using BFC as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Neuraxon

Curated by ChEMBL
LigandPNGBDBM50355313(CHEMBL1835116)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP3A4 using BQ as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2013
Entry Details Article
PubMed