BDBM50355253 CHEMBL1834651

SMILES FC(F)(F)c1ccc2onc(NCC(=O)NC3CN(C3)[C@H]3CC[C@H](CC3)c3ccc4OCOc4c3)c2c1

InChI Key InChIKey=HQGJCOXCZNLUFA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50355253   

TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50355253(CHEMBL1834651)
Affinity DataIC50: 36nMAssay Description:Displacement of [125I]-MCP1 from human CCR2 receptor in THP1 cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetC-C chemokine receptor type 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50355253(CHEMBL1834651)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human CCR2 receptor in THP1 cells assessed as inhibition of MCP1-induced chemotaxis after 3 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50355253(CHEMBL1834651)
Affinity DataIC50: 1.90E+3nMAssay Description:Displacement of [3H]-astemizole from human ERG in HEK293 cells after 1 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2012
Entry Details Article
PubMed